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What is Liposomal Anti-Parasitic Medicine?

Liposomal anti-parasitic medicine is an advanced form of drug delivery where a standard anti-parasitic active ingredient (like ivermectin, fenbendazole and nitazoxanide) is encapsulated within tiny, bubble-like structures called liposomes.

Liposomes are spherical vesicles made from phospholipids, the same molecules that make up human cell membranes. This unique structure is the key to the technology's advantages.

How It Works: The Liposome Advantage

Think of liposomes as microscopic, protective delivery trucks. Here’s how they improve upon conventional anti-parasitic drugs:

1. Enhanced Absorption: Many anti-parasitic drugs are poorly absorbed in the gut or broken down by stomach acid. Liposomes protect the drug during its journey through the digestive system, allowing more of the active ingredient to be absorbed into the bloodstream.

2. Increased Bioavailability: This is the most significant benefit. "Bioavailability" refers to the percentage and rate of the drug that successfully reaches the systemic circulation. By improving absorption and protecting the drug, liposomal encapsulation can significantly increase bioavailability. This means a lower dose can achieve the same therapeutic effect as a higher dose of a conventional form.

3. Targeted Delivery: While less relevant for systemic parasitic infections, liposomes have a natural tendency to accumulate in certain tissues. This can potentially help target parasites residing in specific organs, like the liver.

4. Reduced Side Effects: By improving the efficiency of the drug, lower doses can often be used. Furthermore, liposomes shield the body from direct, immediate contact with the full drug dose, which can mitigate common gastrointestinal side effects like nausea or stomach upset.